By culturing the culture and the culture of immortalized cells E1 method for increasing the yield of product obtained from the culture

摘要

The present invention, in the embryonic retinoblastoma cells immortalized by adenovirus E1 sequences, and provides a method of culturing a PER.C6 (TM) cell-derived cells, preferably, to improve the product yields from the cells there. Culture having a very high cell densities and supply plan of the cells is provided, as a result, products such as recombinant antibodies can be obtained in high yield.