首页> 外国专利> Drug efficacy prediction method and drug efficacy prediction device for anti-TNFα antibody for rheumatoid arthritis

Drug efficacy prediction method and drug efficacy prediction device for anti-TNFα antibody for rheumatoid arthritis

机译:类风湿关节炎抗TNFα抗体的药效预测方法及药效预测装置

摘要

The anti-TNFα antibody drug for rheumatoid arthritis can be predicted with high certainty and convenience, and the activity of rheumatoid arthritis after administration of the drug can be predicted. The provision of a drug efficacy prediction method and a drug efficacy prediction device for anti-TNFα antibodies against rheumatoid arthritis that can avoid useless side effects by administering the drug to a case that works more reliably. The method for predicting the efficacy of an anti-TNFα antibody drug for rheumatoid arthritis according to the present invention comprises a step of measuring the content of ADAMTS5 in a sample derived from a subject, and the anti-TNFα antibody against rheumatoid arthritis using the content of ADAMTS5 as an index. Evaluating whether the drug is effective.
机译:可以高度确定和方便地预测用于类风湿性关节炎的抗TNFα抗体药物,并且可以预测给药后的类风湿性关节炎的活性。提供了针对类风湿性关节炎的抗TNFα抗体的药效预测方法和药效预测装置,该药效预测方法和药效预测装置可以通过对更可靠地起作用的病例给药来避免无用的副作用。根据本发明的预测抗TNFα抗体药物对类风湿性关节炎的功效的方法包括以下步骤:测量来自受试者的样品中ADAMTS5的含量,以及使用该含量测量针对类风湿性关节炎的抗TNFα抗体的步骤。以ADAMTS5作为索引。评估药物是否有效。

著录项

  • 公开/公告号JPWO2010038840A1

    专利类型

  • 公开/公告日2012-03-01

    原文格式PDF

  • 申请/专利权人 株式会社ケイティーバイオ;

    申请/专利号JP20100531910

  • 发明设计人 津坂 憲政;竹内 勤;

    申请日2009-10-01

  • 分类号C12Q1/68;C12M1;C12M1/34;C12N15/09;A61P29;A61K39/395;A61P19/02;C07K16/24;

  • 国家 JP

  • 入库时间 2022-08-21 17:35:32

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