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Recombinant Measles Virus Useful as a Bivalent Vaccine Against Measles and Nipah Infections
Recombinant Measles Virus Useful as a Bivalent Vaccine Against Measles and Nipah Infections
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机译:重组麻疹病毒可用作针对麻疹和Nipah感染的二价疫苗
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摘要
Provided herein is a vaccine which is safe and effective against Nipah virus infection and a vector which is used in the manufacture of this vaccine and to provide a bivalent vaccine which exhibits an excellent preventive effect against measles virus and Nipah virus infection and which eliminates complexity at the time of inoculation. Also provided is a recombinant measles virus in which is inserted a gene which encodes a protein involved in preventing Nipah infection into the measles virus genome. The protein involved in preventing Nipah virus infection is preferably G protein or F protein which is a membrane protein. Also provided is a bivalent vaccine against measles and Nipah virus infection which contains the recombinant measles virus. Also provided is a method of manufacturing a vaccine against Nipah virus infection
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