CHROMATOGRAPHIC PEAK IDENTIFICATION USING BOOTSTRAP REPLICATION OBJECT ORIENTED SYSTEM AND METHOD

摘要

A computerized system and method analyzes chromatographic data by determining at least one data point in the graph of a set of chromatographic data according to a predetermined criteria. A set of deviations is calculated from the data point in each set of chromatographic data. A set of replicated data points is created wherein each replicate data point is calculated by combining each data point and a randomly selected deviation. Once the replicated data is created, statistical analysis may be performed on the set of replicate data points. The replication of data points uses random selection with replacement. The deviations may be calculated by a function of a random percentile number and a calculated standard deviation from a data point. A first and second derivative of the chromatograph may be calculated for each data point. The data points may further be smoothed.