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NOVEL BIOMARKER FOR LIVER CANCER AND APPLICATIONS FOR SAME

机译:新型肝癌生物标志物及其应用

摘要

The present invention relates to the elucidation of a gene that can act as a novel marker for liver cancer diagnosis and to diagnostic and prognostic measurements of liver cancer using the same. More specifically, it relates to a diagnosis kit that enables diagnostic and prognostic measurement of a liver cancer using a preparation that measures expression levels of at least one gene selected from a group of liver cancer diagnosis markers consisting of S100P, NK4, CCL20, CSPG2, PLAU, MMP12, ESM-1, ABHD7, HCAPG, CXCL-3, Col5A2, MAGEA, GSN, CDC2, CST1, MELK, ATAD2, FAP and MSN and/or a method for diagnostic and prognostic measurement of liver cancer using the same. These have been discovered using normal liver tissues and liver cancer tissues collected from the same liver cancer patient of the present invention and represent the markers whose accuracy and reliability have been greatly improved as markers of liver cancer. The markers of the present invention can be used for the accurate diagnosis and prognosis of liver cancer.
机译:本发明涉及可以用作肝癌诊断的新标记的基因的阐明,并涉及使用该基因的肝癌的诊断和预后测量。更具体地,本发明涉及一种诊断试剂盒,该诊断试剂盒使用能够测量选自由S100P,NK4,CCL20,CSPG2, PLAU,MMP12,ESM-1,ABHD7,HCAPG,CXCL-3,Col5A2,MAGEA,GSN,CDC2,CST1,MELK,ATAD2,FAP和MSN和/或使用它们的肝癌诊断和预后测量方法。这些是使用从本发明的同一肝癌患者收集的正常肝组织和肝癌组织发现的,并且代表了其准确性和可靠性已大大改善的标志物作为肝癌标志物。本发明的标记物可用于肝癌的准确诊断和预后。

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