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Process For Preparing Prophyrin Derivatives, Such As Protoprophyrin (IX) And Synthesis Intermediates

机译：制备原卟啉（IX）和合成中间体的原卟啉衍生物的方法

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摘要

The present invention relates to a process for preparing a porphyrin of formula (I), optionally in the form of a salt with an alkali metal and/or in the form of a metal complex:; embedded image

;in which:R and R′ are as defined in claim 1, comprising:a step of condensation, in an acidic medium, between a dipyrromethane of formula (II):; embedded image

;in which R′b is as defined above for (I),and a dipyrromethane of formula (III):; embedded image

;in which R″ is as defined in claim 1, and also the compounds of formula (III).

机译：本发明涉及一种制备式（I）的卟啉的方法，该卟啉任选以与碱金属的盐的形式和/或以金属络合物的形式： “嵌入式图像”

;其中： R和R'如权利要求 1 所定义包括：在酸性介质中，式（II）的二吡咯甲烷与甲烷缩合的步骤： ; ;其中R'b如上文（I）所定义，和式（III）的二吡咯甲烷：; ;其中R”如权利要求 1 所定义，以及式（III）化合物。 展开▼

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公开/公告号US2011306761A1

专利类型

公开/公告日2011-12-15

原文格式PDF

申请/专利权人 PIERRE MARTIN;MARKUS MUELLER;DIRK SPIELVOGEL;DIETMAR FLUBACHER;ANDREAS BOUDIER;
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申请/专利号US201113218149

发明设计人 PIERRE MARTIN;MARKUS MUELLER;DIRK SPIELVOGEL;DIETMAR FLUBACHER;ANDREAS BOUDIER;
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申请日2011-08-25

分类号C07F15/02;C07F5;C07F15/04;C07F3/06;C07D207/34;C07F15/06;C07F3/04;C07F3/02;C07D403/06;C07D487/22;C07F15;

国家 US

入库时间 2022-08-21 17:31:57

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