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Process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

机译:官能化苯并环丁烯的制备方法及其在伊伐布雷定及其与可药用酸加成盐的合成中的应用

摘要

Process for the preparation of compounds of formula (IV):; embedded image wherein R1-R6 are as defined in the specification.;Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.
机译:制备式(IV)化合物的方法: “嵌入式图像” 其中R 1 -R 6 如说明书中所定义。;在合成伊伐布雷定,其与可药用酸的加成盐及其水合物中的应用。

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