首页> 外国专利> Method for measuring glycoprotein, method for examining liver disease, reagent for quantitative determination of glycoprotein, and glycan-marker glycoprotein as an index for clinical conditions of liver disease

Method for measuring glycoprotein, method for examining liver disease, reagent for quantitative determination of glycoprotein, and glycan-marker glycoprotein as an index for clinical conditions of liver disease

机译:糖蛋白的测定方法,肝病的检查方法,糖蛋白的定量测定试剂以及作为肝病的临床状况指标的聚糖标记糖蛋白

摘要

An object of the present invention is to provide a method for measuring a glycan-marker glycoprotein, by which liver disease can be detected with higher accuracy than is possible with conventional methods. Also, an object of the present invention is to provide a method for examining liver disease, by which liver disease can be detected with higher accuracy than is possible with conventional methods. Disclosed is a method for measuring at least one glycoprotein selected from alpha-1-acid glycoprotein (AGP) and Mac-2-binding protein (M2BP) contained in a sample collected from a subject, comprising: measuring AGP binding to a first lectin selected from AOL and MAL, when the glycoprotein is AGP; and measuring M2BP binding to a second lectin selected from WFA, BPL, AAL, RCA120, and TJAII, when the glycoprotein is M2BP.
机译:本发明的目的是提供一种测量聚糖标记糖蛋白的方法,与常规方法相比,通过该方法可以以更高的准确性检测肝脏疾病。另外,本发明的目的是提供一种检查肝脏疾病的方法,通过该方法可以比传统方法更准确地检测肝脏疾病。本发明公开了一种用于测量从受试者收集的样品中包含的选自α-1酸性糖蛋白(AGP)和Mac-2-结合蛋白(M2BP)中的至少一种糖蛋白的方法,该方法包括:测量与所选择的第一凝集素的AGP结合。当糖蛋白为AGP时,来自AOL和MAL;当糖蛋白为M2BP时,测量M2BP与选自WFA,BPL,AAL,RCA120和TJAII的第二种凝集素的结合。

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