NOVEL PREPARATION METHOD OF HUMAN METABOLITES OF SIMVASTATIN OR LOVASTATIN USING BACTERIAL CYTOCHROME P450 AND COMPOSITION THEREFOR

摘要

A method of producing human metabolites of simvastatin or lovastatin, and more particularly, a method of producing human metabolites of simvastatin and lovastatin by using bacterial cytochrome P450 BM3(CYP102A1) or mutants thereof, and a composition and kit therefor.