Method and apparatus for in situ drug delivery during distraction osteogenesis

摘要

A device and technique for the performance of distraction osteogenesis of bone with controlled drug delivery using a bead chain consisting of two bands and a series of drug delivery capsules placed in a precise manner such that the relative motion of the bone segments brings the wires, pins, or screws into contact with the capsules and divides them. This action sequentially delivers the drug to the distraction zone throughout the distraction osteogenesis process.