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Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
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机译:免疫调节剂家族称为白细胞免疫球蛋白样受体(LIR)
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摘要
A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridize to oligonucleotide probes having defined sequences, processes for producing polypeptides of the LIR family, and antagonistic antibodies to LIR family members. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.
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