embedded image in which R1, R2, R5, R6, R7, R11, X, and m are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity."/> Substituted 7,8,9,10-tetrahydro-5H-dipyrido1,2-a:3′,2′-epyrazin-6(6aH)-ones
首页> 外国专利> Substituted 7,8,9,10-tetrahydro-5H-dipyrido1,2-a:3′,2′-epyrazin-6(6aH)-ones

Substituted 7,8,9,10-tetrahydro-5H-dipyrido1,2-a:3′,2′-epyrazin-6(6aH)-ones

机译:取代7,8,9,10-四氢-5H-联吡啶[1,2-a:3',2'-e]吡嗪-6(6aH)-ones

摘要

Disclosed are compounds of the following formula:; embedded image in which R1, R2, R5, R6, R7, R11, X, and m are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity.
机译:公开了下式的化合物: “嵌入式图像” 其中R 1 ,R 2 ,R 5 ,R 6 ,R 7 ,R 11 ,X和m在规范中定义。还公开了药物组合物,试剂盒和制品,其包含化合物,可用于制备化合物的方法和中间体,以及使用该化合物治疗与PARP活性有关的疾病,病症和病状的方法。

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