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Methods of treating disease with nitric oxide (NO)-releasing polymers and soluble no-releasing nitrosamines

机译:用释放一氧化氮(NO)的聚合物和可溶性不释放亚硝胺治疗疾病的方法

摘要

The invention provides NO-releasing polymers and low molecular weight NO-releasing compounds which may be used to for the treatment of medical conditions associated with NO-deficiency. The NO-releasing polymers or the low molecular weight NO-releasing compounds may also be incorporated into medical devices. The invention further provides methods of controlled release of NO for the treatment of diseases and disorders associated with NO-deficiency, wherein the treatment includes systemic or local administration of the NO-releasing polymers or the low molecular weight NO-releasing compounds.
机译:本发明提供了NO释放聚合物和低分子量NO释放化合物,其可用于治疗与NO缺乏相关的医学病症。释放NO的聚合物或低分子量的释放NO的化合物也可以掺入医疗设备中。本发明进一步提供了用于治疗与NO缺乏相关的疾病和病症的NO的控释方法,其中所述治疗包括全身或局部施用释放NO的聚合物或低分子量释放NO的化合物。

著录项

  • 公开/公告号US8062656B2

    专利类型

  • 公开/公告日2011-11-22

    原文格式PDF

  • 申请/专利权人 JUSTIN D. OH-LEE;DILLIP K. MOHANTY;

    申请/专利号US20080105857

  • 发明设计人 JUSTIN D. OH-LEE;DILLIP K. MOHANTY;

    申请日2008-04-18

  • 分类号A61K31/765;A61K31/135;A61F2/86;A61F2;A61P15;A61P11;A61P25;A61P25/18;A61P9;

  • 国家 US

  • 入库时间 2022-08-21 17:26:16

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