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Pyrrole derivative having, as substituents, ureido group, aminocarbonly group and bicyclic group which may have substituent
Pyrrole derivative having, as substituents, ureido group, aminocarbonly group and bicyclic group which may have substituent
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机译:具有脲基,氨基碳原子基团和可以具有取代基的双环基团作为取代基的吡咯衍生物
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摘要
A compound represented by the following formula (1) or a salt thereof:; The compound has an inhibitory activity on the production of interleukin-6, and is therefore useful as a therapeutic agent for a disease associated with interleukin-6, ocular inflammatory diseases and the like. In the formula, R1 represents a halogen atom, a hydrogen atom, a lower alkyl group which may have a substituent, a formyl group, or a lower alkylcarbonyl group which may have a substituent, R2 represents a bicyclic hydrocarbon group which may have a substituent or a bicyclic heterocyclic group which may have a substituent, R3 represents a hydrogen atom, a lower alkyl group which may have a substituent, an aryl group which may have a substituent, or an acyl group.
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