首页> 外国专利> Derivatives of 3 - (heteroaryl amino) - 1,2,3,4 - tetrahydro - 9h carbazole, modulators of prostaglandin D2 Receptors, Pharmaceutical compositions containing them and Use thereof in the treatment of allergic or autoimmune Disorders such as Asthma.

Derivatives of 3 - (heteroaryl amino) - 1,2,3,4 - tetrahydro - 9h carbazole, modulators of prostaglandin D2 Receptors, Pharmaceutical compositions containing them and Use thereof in the treatment of allergic or autoimmune Disorders such as Asthma.

机译:3-(杂芳基氨基)-1,2,3,4-四氢-9h咔唑的衍生物,前列腺素D2受体的调节剂,含有它们的药物组合物及其在治疗过敏性或自身免疫性疾病(如哮喘)中的用途。

摘要

Claim 1: a compound of formula (1) wherein R1 represents Hydrogen, alkyl c1-4 alkoxy, c1-4, halogeno, trifluoromethyl or trifluoromethoxy; R2 represents Hydrogen, c1-4 alkyl, alkoxy alkyl 2 - C1 - C2 - 3, fluoroalquilo c1-4 alkyl or cycloalkyl C1 - C3 - 6 - 2; and R3 represents a group h Eteroarilo insustituido or mono -, di - or tri substitutedWhere the substituents are chosen independently of the Group comprising Halogen c1-4 alkyl, cycloalkyl, c3-6, c1-4 alkoxy, fluoroalquilo c1-4 and phenyl; or a Salt of the compound.
机译:权利要求1:式(1)化合物,其中R1代表氢,烷基C1-4烷氧基,C1-4,卤代,三氟甲基或三氟甲氧基; R 2代表氢,C 1-4烷基,烷氧基烷基2-C 1 -C 2-3,氟代芳基C 1-4烷基或环烷基C 1 -C 3-6-2; R3代表hEsteroarilo insustituido或单,二或三取代的基团,其中取代基的选择独立于卤素C1-4烷基,环烷基,C3-6,C1-4烷氧基,氟代烷基C1-4和苯基。或化合物的盐。

著录项

  • 公开/公告号AR080703A1

    专利类型

  • 公开/公告日2012-05-02

    原文格式PDF

  • 申请/专利权人 ACTELION PHARMACEUTICALS LTD.;

    申请/专利号AR2011P100914

  • 发明设计人

    申请日2011-03-21

  • 分类号C07D209/88;A61K31/403;A61P37/00;A61P11/02;A61P11/06;A61P27/04;

  • 国家 AR

  • 入库时间 2022-08-21 17:25:34

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