Uses of Thrombin Receptor Antagonist Compounds in Prophylaxis of Cardiopulmonary Surgery Complications

摘要

USES OF THROMBINE RECEPTOR ANTAGONIST COMPOUNDS IN THE PROPHYLAXIS OF COMPLICATIONS OF CARDIOPULMONARY SURGERY. The present invention relates to methods of preventing, inhibiting, or ameliorating complications associated with cardiopulmonary bypass surgery by the use of a thrombin receptor antagonist compound. Among the thrombin receptor antagonist compounds useful in these methods are those of Formulas (1) and (II), described herein. Examples of such thrombin receptor antagonists include: