FORMULATIONS WHICH STABILIZE POLYESACARIDE PROTEIN CONJUGATES, COMPOSITIONS OF STREPTOCOPIC C5A PEPTIDASE AND COMPOSITION OF N. MENINGITIDIS PROTEIN 2086, AS FORMULATIONS THAT INHIBIT A SILDUCED INDUGED DEGRED AGGREGATE INGREDIENTS C5A STREPTOCIC PEPTITY COMPOSITION AND SILICON-INDUCED AGGREGATION OF A N.MENINGITIDI PROTEIN 2086 COMPOSITION

摘要

FORMULATIONS WHICH STABILIZE POLESACARIDE PROTEIN CONJUGATES, STREPTOCTIC C5A PEPTIDASE COMPOSITIONS, AND N. MENINGITID PROTEIN COMPOSITION, AS WELL AS FORMULATIONS INDUCING A SILDUCED INDOGENED CONDUCTION Composition of streptococcal C5A PEPTIDASE AND SILICON-INDUCED AGGREGATION OF A N. MENINGITIDI PROTEIN 2086 COMPOSITION. The present invention relates to a continuing need in the art to improve the stability of immunogenic compositions such as polysaccharide-protein conjugates and protein immunogens. The invention broadly relates to novel formulations which stabilize and inhibit precipitation of immunogenic compositions. More particularly, the invention described herein addresses a need in the art for formulations which stabilize and inhibit particle formation (e.g., aggregation, precipitation) of immunogenic compositions which are processed, developed, formulated, manufactured and / or stored in container media such as fermenters, bioreactors, vials, bags, syringes, rubber stoppers, tubing and the like.