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Multivalent meningococcal vaccine consisting of a polysaccharide / protein conjugate
Multivalent meningococcal vaccine consisting of a polysaccharide / protein conjugate
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机译:由多糖/蛋白质结合物组成的多价脑膜炎球菌疫苗
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摘要
The present invention describes a combined vaccine that offers broad protection against meningococcal disease caused by the pathogenic bacterial Neisseria meningitidis. The vaccine is comprised of four distinct polysaccharide-protein conjugates that are formulated as a single dose of vaccine. Purified capsular polysaccharides from Neisseria meningitidis serogroups A, C, W-135, and Y are chemically activated and selectively attached to a carrier protein by means of a covalent chemical bond, forming polysaccharide-protein conjugates capable of eliciting long-lasting immunity to a variety of N. meningitidis strains in children as well as adults,
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