Appropriate ingredients for the treatment of BCR-ABL, c-kit, DDR1, DDR2 or PDGF-R radiation activation disorders and other disease conditions

摘要

The invention refers to a system of pyridine amine benzene zamida (I) formula for the treatment of diffuse disorders, especially solid or liquid tumors. Under this system, currently defined active molecules or pharmaceutically acceptable salt can be used for the treatment of diffuse disorders, And other pathological conditions regulated by the activity of BCR-ABL's undecylin, c-kit cell transmembrane thyroid hormone receptor or DDR1,DDR2 (domain receiver 2),O PDGF-R (platelet growth factor receptor),1. Pyridine amine amphetamine amphetamine in equation 1 and alternative acceptable drug vehicles are distributed in fruit preparation.