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CONFORMATIONALLY RESTRICTED POLYAMINE ANALOGS AND USES THEREOF

机译：构象受限的聚酰胺类似物及其用途

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摘要

Novel conformationally restricted polyamine analogs are provided, as well as compositions comprising these novel polyamine analogs. Methods of using the novel polyamine analogs in treatment of diseases such as cancer are also provided. Also provided is a method of delivering these analogs specifically to tumor cells by covalently attaching polyamine analogs to porphyrin compounds, along with novel polyamine-porphyrin covalent conjugates.

机译：提供了新颖的构象受限的多胺类似物，以及包含这些新颖的多胺类似物的组合物。还提供了使用新型多胺类似物治疗疾病例如癌症的方法。还提供了通过将多胺类似物与新颖的多胺-卟啉共价缀合物共价附接至卟啉化合物而将这些类似物特异性递送至肿瘤细胞的方法。

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公开/公告号IL146127A

专利类型
公开/公告日2011-11-30

原文格式PDF
申请/专利权人 PROGEN PHARMACEUTICALS INC.;SLIL BIOMEDICAL CORPORATION;
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申请/专利号IL20010146127
发明设计人
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申请日2001-10-23
分类号A61K31/13;A61K31/132;A61K31/137;A61K31/155;A61K31/40;A61K31/409;A61K38;A61K47/48;A61P1/04;A61P9/10;A61P17/02;A61P17/06;A61P25/08;A61P25/28;A61P31/04;A61P33;A61P35;C07C45/46;C07C67/343;C07C211/18;C07C211/22;C07C211/23;C07C211/36;C07C215/14;C07C251/18;C07C257/18;C07D207/34;C07D219/10;C07D235/18;C07D295/185;C07D307/79;C07D307/92;C07D311/92;C07D317/70;C07D487/22;C07D493/04;C07K5/103;C07K7/06;
国家 IL
入库时间 2022-08-21 17:24:50

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