NON MURINE ANTIBODIES FOR REDUCING BONE LOSS ASSOCIATED WITH METASTATIC CANCER AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

摘要

M-CSF antagonists are provided, along with pharmaceutical compositions containing a M-CSF antagonist, kits containing a pharmaceutical composition, methods of preventing and treating bone metastases in a subject afflicted with metastatic cancer, methods of screening for M-CSF antagonists, and uses of M-CSF in medicine and preparing medicaments for preventing and treating bone metastases and tumor growth.