COMBINATION OF GLYCOISOFORMS FOR THE TREATMENT OR PREVENTION OF SEPSIS, TRANSGENIC CELL LINE PRODUCING ERYTHROPOIETIN GLYCOISOFORMS, PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMBINATION, PROCEDURES TO OBTAIN THE CELL LINE AND PROCEDURES TO PRODUCE SUCH COMBINATION OF GLYCOISOFORMS

摘要

Combination of erythropoietin glycoisoforms, wherein such glycoisoforms may comprise a quantity of sialic acid ranging from 4 to 10 molecules of sialic acid per molecule of erythropoietin, the combination of glycoisoforms can be used for the treatment or prevention of sepsis, a pharmaceutical composition comprising such combination, a cell line producing a combination of erythropoietin glycoisoforms, procedures to obtain the cell line, procedure to produce such combination of glycoisoforms and methods of treatment and prevention of sepsis.