POLYPEPTIDES WITH INCREASED SIALIC ACID CONTENT, ENHANCED ANTI-INFLAMMATORY ACTIVITY AND DECREASED CYTOTOXIC ACTIVITY, PHARMACEUTICAL FORMULATIONS COMPRISING THE SAME AND METHOD FOR PREPARING THE SAME

摘要

The invention provides a polypeptide containing at least one IgG Fc region, said polypeptide having a higher anti-inflammatory activity and a lower cytotoxic activity as compared to an unpurified antibody and methods of production of such polypeptide.