首页> 外国专利> COMPOSITION AND PREPARATION OF HERBAL LIPOSOMES FOR ANTIASTHMATIC ACTIVITY-WITH INCREASED EFFICACY AND REDUCED DOSE'.

COMPOSITION AND PREPARATION OF HERBAL LIPOSOMES FOR ANTIASTHMATIC ACTIVITY-WITH INCREASED EFFICACY AND REDUCED DOSE'.

机译:具有提高功效和减少剂量的抗麻醉活性的草本脂质体的组成和制备”。

摘要

"Composition and preparation of herbal liposomes for antiasthmatic activity - with increased efficacy and reduced dose ," gives the maximum relief in asthma with maximum safety and no side effects as these are prepared from the herbal extracts. Herbal liposomes combination formulation i.e. liposomes of A.lebbeck and A.vasica are first time prepared and given to have maximum synergistic effect, maximum pharmacological activity with reduced dose of extracts by 20% by liposomal carriers. Both types of liposomes are separately characterized, evaluated for different parameters like size, shape, Polydispersity index, zeta potential, entrapment efficiency, stability and various pharmacological screening activities are also performed to prove effectiveness of formulation. Drug-drug interaction study done by FTFR. standardization of formulation performed by HPTLC. After passing all above parameters, Novel herbal liposomes formulation acts as a golden link between natural source and novel drug delivery in effective treatment of asthma.
机译:“具有抗哮喘活性的草药脂质体的组成和制备-具有更高的功效和更低的剂量,”这是从草药提取物中制备的,可最大程度地缓解哮喘,并具有最大的安全性且无副作用。首次制备草药脂质体组合制剂,即A.lebbeck和A.vasica的脂质体,使其具有最大的协同作用,最大的药理活性,并且脂质体载体可使提取物的剂量减少20%。对两种类型的脂质体分别进行表征,评估不同参数,如大小,形状,多分散指数,ζ电势,包封率,稳定性和各种药理筛选活性,以证明制剂的有效性。 FTFR进行的药物相互作用研究。 HPTLC执行的配方标准化。通过以上所有参数后,新型草药脂质体制剂可有效治疗哮喘,成为天然来源与新型药物输送之间的黄金纽带。

著录项

  • 公开/公告号IN2011MU02170A

    专利类型

  • 公开/公告日2011-11-18

    原文格式PDF

  • 申请/专利权人

    申请/专利号IN2170/MUM/2011

  • 申请日2011-07-29

  • 分类号A61K33;

  • 国家 IN

  • 入库时间 2022-08-21 17:24:03

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