AN IMPROVED PROCESS FOR THE SYNTHESIS OF ALKYL / ARALKYL (2S)-2-(TERT-BUTOXYCARBONYL)-AMINO-2--8-AZABICYCLO3.2.1OCT-3-YL-EXO-ACETATE AND ANALOGS THEREOF: KEY INTERMEDIATES FOR THE PREPARATION OF DPPIV INHIBITORS

摘要

An improved process for the synthesis of intermediates like Alkyl/Aralkyl (2S)-2-(tert-butoxycarbonyl)-amino-2-[-8-azabicyclo[3.2.1]oct-3-yl]-exo-acetate and analogs thereof which are useful in the synthesis of Dipeptidyl peptidase-IV (DPPIV) inhibitors.