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(2-Carbamotioylhydrazone)propionato(2-)-(4-aminobenzenesulfonamide)copper, manifesting antimicrobial activity against bacteria of the genus Bacillus cereus

机译:[(2-氨基甲酰基hydr)丙酰(2-)]-(4-氨基苯磺酰胺)铜,对蜡状芽孢杆菌属细菌具有抗菌活性

摘要

The invention relates to chemistry and medicine, namely to a coordinative compound of biologically active copper from the class of thiosemicarbazonates.Summary of the invention consists in the synthesis of a new compound of copper with two biologically active ligands [(2-carbamotioylhydrazone)propionato(2-)]-(4-aminobenzenesulfonamide)copper of formula:The compound manifests high bacteriostatic and bactericidal activity against bacteria of the genus Bacillus cereus. Due to these properties it can be used in medicine and veterinary medicine as an antimicrobial drug.The result consists in that the new compound manifests antimicrobial activity against bacteria of the genus Bacillus cereus 33…156 times higher than furacin and approximately 1·105 times higher than the structural analogue - the copper complex with 2-formylpyridine thiosemicarbazone.
机译:本发明涉及化学和医学,即涉及一种硫代半氨基甲酸酯类的生物活性铜的配位化合物。发明内容概述在于合成具有两个生物活性配体[(2-氨基甲酰基酰))丙酮(式:2-)]-(4-氨基苯磺酰胺)铜:该化合物对蜡状芽孢杆菌属的细菌表现出高抑菌和杀菌活性。由于这些特性,它可以在医学和兽医学中用作抗微生物药物。其结果是,该新化合物对蜡状芽孢杆菌属的细菌表现出抗微生物活性,比呋喃星高33…156倍,高约1·105倍。比结构类似物-与2-甲酰基吡啶硫半碳zone的铜配合物。

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