The subject of the invention is an orally administerable pharmaceutical preparation containing a combination of biotechnologically produced human recombinant insulin and/or modified insulin or an analogue and/or derivative thereof, a protease inhibitor and a high molecular weight (natural) protein. The invention relates to a method for the production of the pharmaceutical preparation as well. The subject of the invention also covers the use of the pharmaceutical preparation and a method for the treatment of diabetes in mammals.
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