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Morphine-6-glucose derivatives and their preparations and use in treatment.
Morphine-6-glucose derivatives and their preparations and use in treatment.
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机译:吗啡-6-葡萄糖衍生物及其制备和治疗用途。
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摘要
The present invention is a derivative of morphine-6-glucose formula (I). In this formula, R1 is an heteroaryl group composed of five links, which is finally replaced by one or more substitutes selected from the halogen atom and tar group (C1-C4),Halogen, hydroxy, halogen (C1-C4),1. Halogenated tar (C1-C4),1. Hydrocarbon (C1-C4),1. Aril acquilo (C1-C4) and arilo are finally replaced by one or more groups selected from the asphalt group (C1-C4);1. Halide (C1-C4),Hydroxyl and hydrocarbon (C1-C4),In the form of an acid base or salt, and the state of a hydrate or solution. The invention also aims at the preparation procedure and treatment application thereof.
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