Ophthalmic compositions comprising povidone-iodine and dexamethasone

摘要

Disclosed is an ophthalmic composition suitable for topical administration to an eye, comprising a mixture of: a) povidone-iodine in a concentration between 0.01 percent and 10 percent by weight, and b) a steroid, wherein the steroid is dexamethasone, and wherein, after a period of one month after mixing the steroid and povidone-iodine to form the composition, the steroid concentration is at least 90 percent by weight of the steroid starting concentration. Also disclosed is the use of a) povidone-iodine and b) a steroid, wherein the steroid is dexamethasone, for the manufacture of an ophthalmic composition suitable for topical administration to an eye. Povidone is also known as 2-Pyrrolidinone, 1-ethenyl-, homopolymer.