首页> 外国专利> A conjugate comprsing the amino acid sequence LPWKPLG for targeting compounds to brain cells, neuronal cells or tumour cells of neuronal or neuroectodermal origin

A conjugate comprsing the amino acid sequence LPWKPLG for targeting compounds to brain cells, neuronal cells or tumour cells of neuronal or neuroectodermal origin

机译:包含氨基酸序列LPWKPLG的缀合物,用于将化合物靶向神经元或神经外胚层来源的脑细胞,神经元细胞或肿瘤细胞

摘要

Disclosed is a conjugate of a peptide or peptidomimetic comprising a sequence or consisting of a sequence of LPWKPLG linked to a moiety selected from a biological active moiety and diagnostic moiety. Also disclosed is the use of said conjugate for the preparation of a medicament for targeting a biological active moiety or a diagnostic moiety across the blood brain barrier to brain cells, to neuronal cells or to tumour cells of neuronal or neuroectodermal origin.
机译:公开了一种肽或拟肽的缀合物,其包含与选自生物学活性部分和诊断部分的部分连接的LPWKPLG的序列或由其组成。还公开了所述缀合物在制备用于跨血脑屏障将生物活性部分或诊断部分靶向脑细胞,神经元细胞或神经元或神经外胚层来源的肿瘤细胞的药物中的用途。

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