METHOD FOR PRODUCING A MIXTURE OF BACTERIOPHAGES AND THE USE THEREOF IN THE THERAPY OF ANTIBIOTIC-RESISTANT STAPHYLOCOCCI

摘要

Disclosed is a method for producing a mixture of bacteriophages, wherein at least two different bacteriophage strains have been reproduced separately, wherein a staphylococcus strain is grown in an preculture with each of strains of a bacteriophage that can lyse staphylococci and is then further reproduced in a main culture, and is then purified, and the different strains are then mixed, characterised in that the mixture of bacteriophages used comprises at least two different serotypes of bacteriophages that lyse specifically bacteria of the species Staphylocuccus whereby the mixture of bacteriophages contains the bacteriophage MP13.3 having the accession number DSM 18722 and the bacteriophage KP3 having the accession number DSM 18723 and in that the bacterial strain that is used for the reproduction of the bacteriophages is a methicillin-sensitive strain of Staphylococcus aureus.