MULTIFUNCTIONAL LINKER PROTEIN CONTAINING AN ANTIBODY AGAINST HEMAGGLUTININ, A CONSERVED INFLUENZA ANTIGEN AND AN IMMUNOSTIMULATING CARRIER BINDING DOMAIN

摘要

Disclosed is a proteinaceous substance comprising (i) at least one hemagglutinin (HA) binding domain (HBD) capable of noncovalently binding to multiple antigenic subtypes of HA, (ii) a conserved influenza protein, or an antigenic fragment thereof, and (iii) an immunostimulating carrier binding domain (IBD).