Pharmaceutical formulation of estriol vaginal Administration

摘要

Refers to a Pharmaceutical composition comprising: (a) whose dosage includes estriol - between 0.02 and 0.07 mg / day; and (b) at least one selected Polymer bioadhesive Polymers, Cellulose, natural Gums, Sodium Alginate, polyoxyethylene, Acrylic Polymers and their blends. The pharmaceutical composition is a gel or cream cremigel mucoadhesive, vaginal Administration.Referring also to the use of estriol in the treatment of urogenital atrophy in Women with a high probability of cardiovascular disease