1.2.4 trinitrotoluene 1.5-A pyridine as enzyme inhibitor

摘要

It refers to the compound produced from [1.2.4] trinitrotoluene [1.5-A] to prepare pyridine (I), wherein a 1 and a 2 are n or C respectively; R1 and R2 are h and hydrocarbon (C1-C4) respectively,Arilo, halogeno et al; R3 is h, hydrocarbon (C1-C4),Cycloquilo, arilo, CN, etc.; X is a link o (CH2) aw (CH2) B, (CH2) aw (CH2) by (CH2) C, a, B and C are respectively 0-3; w e, each is - co -.- that is...-SO2...-CH2...There are others - [1,2,4,4,4,4]]] triphenylene [1,3 - [1,3 - [1,3 - [1,3]] {2 - [4 - (2-morfolin-4-il-etoxi) - phenyl amide - [1,2,4] triazole [1, 5-a) pyridine-6-il} - phenol, etc. These compounds are used in the treatment of myocardial infarction, cancer, arthritis, retinitis, glaucoma and other aspects of enzyme inhibitors.