HYDROGEL CALCIUM PHOSPHATE NANOCOMPOSITE FOR SUBSTITUTING BONE TISSUE

摘要

The invention relates to medicine, namely to compositions used in orthopedics for substituting the areas of the injured bones and in dentistry for filling microcanals in the teeth. A hydrogel calcium phosphate nanocomposite contains three-dimensional mesh of hydrogel matrix produced as a result of copolymerization of acryl monomers (acrylamide, acrylonitrile) with bifunctional cross-linking monomer N,N'-methylene bisacrylamide. The pores of the matrix 5-100 nm in size contain nanoparticles of hydroxylapatite and calcium phosphate compounds possessing high reactivity.