METHODS FOR EFFECTING REGRESSION OF TUMOR MASS AND SIZE IN A METASTASIZED PANCREATIC TUMOR

摘要

THE PRESENT INVENTION RELATES GENERALLY TO METHODS OF INHIBITING ANGIOGENESIS IN A PATIENT BY ADMINISTERING AN EFFECTIVE ANGIOGENESIS-INHIBITING AMOUNT OF A THROMBIN INHIBITOR, AND TO THE TREATMENT OF DISEASE STATES THAT RESULT FROM UNCONTROLLED CELL PROLIFERATION BY ADMINISTERING A THROMBIN INHIBITOR ALONE OR CO-ADMINISTERING A THROMBIN INHIBITOR WITH AN ANTICANCER OR CYTOTOXIC AGENT. SPECIFICALLY, THE THROMBIN INHIBITORS USED IN THE METHODS OF THE PRESENT INVENTION ARE HIRUDINS.