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use of inhibitors of histone - deacetilasi for the treatment of syndromes mieloproliferative philadelphia - negative
use of inhibitors of histone - deacetilasi for the treatment of syndromes mieloproliferative philadelphia - negative
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机译:组蛋白-去乙酰乙酸抑制剂在治疗骨髓增生性费城综合征中的应用-阴性
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摘要
The use of substances capable of inhibiting one or more enzymes of the histone deacetylase family (histone deacetylase inhibitors) for the therapeutic treatment of Philadelphia-negative myeloproliferative syndromes (polycythemia vera, essential thrombocythemia or idiopathic myelofibrosis) is described. The dosage of the above-mentioned substances is significantly lower than that normally used for the care of other tumor syndromes and may be from 10 to 150 mg/day/patient.
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