首页>
外国专利>
chemical synthesis of new heterocyclic fotochemioterapici agents with antiproliferative activity, including that of nature tumour
chemical synthesis of new heterocyclic fotochemioterapici agents with antiproliferative activity, including that of nature tumour
展开▼
机译:化学合成新的具有抗增殖活性的杂环光化学治疗剂,包括自然肿瘤
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention concerns the synthesis of new analogs of angelicins, pyrrolo [3,2-h]quinoline, for the treatment of pathologies having hyperproliferative character included those having neoplastic nature. The treatment is based on the combined action of pyrrolo [3,2-h]quinolines and UV-A light, through a clinical approach defined as PUVA (psoralen-UVA light). The most important feature of these compounds is that they exert their remarkable photoxicity without any DNA damage, which is the main origin of the side effects of the PUVA therapy.
展开▼