首页> 外国专利> PIPERIDINE AND PYRROLIDIN BETA SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER DISEASE

PIPERIDINE AND PYRROLIDIN BETA SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER DISEASE

机译:哌啶和吡咯烷酮分泌酶抑制剂用于治疗老年痴呆症

摘要

The present invention is directed to compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
机译:本发明涉及式(I)的化合物,其为β-分泌酶的抑制剂并且可用于治疗涉及β-分泌酶的疾病,例如阿尔茨海默氏病。本发明还涉及包含这些化合物的药物组合物,以及这些化合物和组合物在治疗涉及β-分泌酶的疾病中的用途。

著录项

  • 公开/公告号AT538796T

    专利类型

  • 公开/公告日2012-01-15

    原文格式PDF

  • 申请/专利权人 MERCK SHARP & DOHME CORP.;

    申请/专利号AT20070838507T

  • 发明设计人 STAUFFER SHAUN;

    申请日2007-09-19

  • 分类号A61K31/55;A61K31/435;A61K31/4439;A61K31/454;A61K31/4545;A61K31/496;A61P25/28;

  • 国家 AT

  • 入库时间 2022-08-21 17:21:50

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