USE OF COMPOUNDS THAT REDUCE ALPHA2-ANTIPLASMIN IN VIVO FOR THE PREPARATION OF A COMPOSITION FOR THE TREATMENT OF ISCHEMIC STROKE

摘要

The present invention relates to a new means for the treatment of focalischemic cerebral infarction (ischemic stroke). It has been found thatreduction of .alpha.2-antiplasmin leads to a significantly smaller focalcerebral infarct size. The invention therefore provides the use of compoundsthat reduce .alpha.2-antiplasmin concentration or activity in vivo, for thepreparation of a therapeutical composition for the treatment of focal cerebralischemic infarction (ischemic stroke).