STREPTOCOCCUS UBERIS PROTEIN, NUCLEIC ACID SEQUENCE ENCODING THE SAME AND ITS USE IN A MASTITIS VACCINE

摘要

The present invention relates to nucleic acid sequences encoding a 22.5 kDStreptococcus uberis protein and to parts of such nucleic acid sequences thatencode an immunogenic fragment of such proteins, and to DNA fragments,recombinant DNA molecules, live recombinant carriers and host cells comprisingsuch nucleic acid sequences or such parts thereof. The invention also relatesto a 22.5 kD Streptococcus uberis protein and immunogenic parts thereofencoded by such sequences. Furthermore, the present invention relates tovaccines comprising such nucleic acid sequences and parts thereof, DNAfragments, recombinant DNA molecules, live recombinant carriers and host cellscomprising such nucleic acid sequences or such parts thereof, proteins orimmunogenic parts thereof and antibodies against such proteins or immunogenicparts thereof. Also, the invention relates to the use of said proteins invaccines and for the manufacture of vaccines. Moreover, the invention relatesto the use of said nucleic acid sequences, proteins or antibodies fordiagnostic or vaccination purposes. Finally the invention relates todiagnostic kits comprising such a nucleic acid, protein or antibodies againstsuch protein.