首页> 外国专利> THERAPEUTIC COMPOSITION COMPRISING EXTRACT OF PHRAGMITIS RHIZOMA AS ACTIVE INGREDIENT, FOR MOISTURIZING SKIN AND TREATING DERMATITIS OR ATOPIC DERMATITIS

THERAPEUTIC COMPOSITION COMPRISING EXTRACT OF PHRAGMITIS RHIZOMA AS ACTIVE INGREDIENT, FOR MOISTURIZING SKIN AND TREATING DERMATITIS OR ATOPIC DERMATITIS

机译:根茎类药物成分组成的治疗性成分,用于保湿和治疗皮肤病或原子性皮肤病

摘要

The present invention relates to a therapeutic composition comprising an extract of Phragmitis Rhizoma as an active ingredient, for moisturizing skin and treating, preventing or alleviating dermatitis or atopic dermatitis. The extract of Phragmitis Rhizoma of the present invention significantly alleviated the symptoms of atopic dermatitis in an atopic animal model NC/Nga mouse obtained by treating the mouse with rat mite antigen to cause atopic dermatitis, reduced the concentration of IgE antibodies in serum, and reduced the amounts of Th1 and Th2 of IFN-γ, IL-4, and IL-10, measured in the axillary lymph node (ANL). In addition, the extract alleviates skin dermatitis induced by means of rat mite extract and DNFB, and has excellent skin moisturizing effects. Therefore, the extract of Phragmitis Rhizoma of the present invention may be developed as a medicine and cosmetic for moisturizing skin or for treating, preventing, or alleviating dermatitis or atopic dermatitis.
机译:本发明涉及一种治疗组合物,其包含根茎芦苇提取物作为活性成分,用于保湿皮肤并治疗,预防或减轻皮炎或特应性皮炎。通过用大鼠螨抗原处理小鼠引起特应性皮炎而获得的特应性动物模型NC / Nga小鼠,本发明的芦苇根瘤提取物显着减轻了特应性皮炎的症状,降低了血清中IgE抗体的浓度,并降低了特应性皮炎的症状。在腋窝淋巴结(ANL)中测得的IFN-γ,IL-4和IL-10的Th1和Th2含量。此外,该提取物减轻了由鼠螨提取物和DNFB诱导的皮肤皮炎,并且具有优异的皮肤保湿效果。因此,本发明的芦根部芦荟提取物可以被开发为用于保湿皮肤或用于治疗,预防或减轻皮炎或特应性皮炎的药物和化妆品。

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