COMPOUND HAVING SILICON-CONTAINING SUBSTITUENT INTRODUCED THERETO, AND SINGLET OXYGEN-GENERATING AGENT AND CANCER THERAPEUTIC COMPRISING SAME

摘要

A compound represented by any of general formulae (I) to (IV) is to be used as the active ingredient of a singlet oxygen-generating agent. In each of R₁ to R₂₀ in general formula (I), R₁ to R₂₄ in general formula (II), R₁ to R₂₈ in general formula (III) and R₁ to R₁₆ in general formula (IV), at least one is a member selected from substituents represented by general formula (i) and (ii) [in general formulae (i) and (ii), Ra, Rb and Rc independently represent a substituent selected from among hydrogen, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, t-butyl, phenyl, methoxy, ethoxy and trimethylsilyl; and n is 1 or greater], and at least one is a substituent represented by general formula (a) [in general formula (a), Ra and Rb independently represent a substituent selected from among hydrogen, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, t-butyl, phenyl, methoxy, ethoxy and trimethylsilyl; and m is 0 or greater].