Method of producing microarray having immobilized double-stranded nucleic acid probe including double-stranded region and single-stranded region

摘要

A method of producing a microarray having an immobilized double-stranded nucleic acid probe comprising a double-stranded region and a single-stranded region, said method includes immobilizing nucleic acids by synthesizing a first single-stranded nucleic acids using photolithography and hybridizing a second single-stranded nucleic acid with the first single-stranded nucleic acid. A microarray with a high spot density and with immobilized long probes may thus be prepared.