PLATELET FACTOR 4 VARIANT FOR THE PROGNOSIS OF CARDIOVASCULAR OUTCOME IN PATIENTS HAVING HEART DISEASE

摘要

The present invention relates to markers for the prognosis of the likely outcome of cardiovascular disease in patients. More particularly, the present invention discloses that low levels of the chemokinedenominated as 'Platelet factor 4 variant' (PF4var) in serum of patients having cardiovascular disease and preserved left ventricular function are predictive for a negative outcome. Hence, the invention relates to methods for the prognosis of cardiovascular disease using PF4var and kits to perform said methods.