SYSTEM AND METHOD FOR INTERSTITIAL PHOTODYNAMIC LIGHT THERAPY IN COMBINATION WITH PHOTOSENSITIZERS

摘要

A method and system for interstitial photodynamic light therapy (IPDT) in combination with photosensitizers is described. A calculation method is used to determine a tissue status used in a feedback loop to control ongoing treatment. Pre-treatment and realtime dosimetry modules for IPDT on whole prostate glandular tissue include target geometry reconstruction, optimization of fiber positions within the geometry, monitoring of light attenuation during treatment and updating individual fiber irradiation times taking variation in tissue light transmission into account. A control device is arranged to restrict delivery of therapeutic light treatment in dependence of at least one attribute of a photodynamic treatment parameter.