RECOMBINANT SINGLE-CHAIN ANTIBODY FRAGMENT NEUTRALIZING THE CYTOLYTIC ACTIVITY OF VAGINOLYSIN

摘要

Recombinant antibody single chain fragment (scFv) was obtained from hybridoma 9B4 (DSM ACC2991) cells using genetic engineering methods. The protein was purified and its specificity to vaginolyzin from G. vaginalis has been shown. The invention examples demonstrate the possibility to use scFv for therapy and prevention purposes of pathology induced by G. vaginalis infection.