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COMPOSITION COMPRISING EXTRACELLULAR VESICLES DERIVED FROM INSIDE A MAMMALIAN BODY AND A USE THEREFOR

机译:包含哺乳动物体内的细胞外囊的组合物及其用途

摘要

The present invention relates to a method or the like for treating or preventing inflammatory diseases and cancers by using extracellular vesicles isolated from inside the body of a mammal. More specifically, provided are: a composition for preventing and/or treating an inflammatory disease, which contains extracellular vesicles isolated from inside the body of a mammal as an active ingredient; and a vaccine for treating and/or preventing an inflammatory disease, which contains the extracellular vesicles as an active ingredient. Also provided is a method or the like for diagnosing the causative substance of a disease or the occurrence or progress of a disease by using the extracellular vesicles. In addition, in the present invention, extracellular vesicles derived from H. pylori isolated from stomach-disease patients can be subjected to inflammatory mediator secretion ability, intravesicular genetic material or protein analysis, vesicle and particularly immune response measurement and the like, thereby diagnosing the causative substance of the stomach disease and the occurrence or progress of the stomach disease.
机译:本发明涉及通过使用从哺乳动物体内分离的细胞外囊泡来治疗或预防炎性疾病和癌症的方法等。更具体地,提供了:用于预防和/或治疗炎症性疾病的组合物,其包含从哺乳动物体内分离出的细胞外囊泡作为活性成分。疫苗和用于治疗和/或预防炎性疾病的疫苗,其包含细胞外囊泡作为活性成分。还提供了通过使用细胞外囊泡来诊断疾病的致病物质或疾病的发生或进展的方法等。另外,在本发明中,源自H的细胞外囊泡。从胃病患者中分离出的幽门螺杆菌可以进行炎症介质分泌能力,囊内遗传物质或蛋白质分析,囊泡特别是免疫反应测定等,从而诊断出胃病的病因和发生或胃病的进展。

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