Method for detecting polymorphism at nucleotide position -1639 of VKORC1 gene, and nucleic acid probe and kit therefor

摘要

A probe for detecting a polymorphism at position -1639 of the VKORC1 gene, the probe comprising an oligonucleotide having a nucleotide sequence having a length of 10 to 50 nucleotides, which nucleotide sequence comprises the nucleotides 80 to 89 of SEQ ID NO: 1 or 2 and has homology to SEQ NO:1 or 2 except that the nucleotide corresponding to the nucleotide at position 80 in SEQ ID NO: 1 or 2 is cytosine, which nucleotide corresponding to the nucleotide at position 80 is labeled with a fluorescent dye.