METHYLATED CODING AND NON-CODING RNA GENES AS DIAGNOSTIC AND THERAPEUTIC TOOLS FOR HUMAN MELANOMA

摘要

Provided herein are methods for the diagnosis and treatment of human melanoma and prediction of early disease genesis to metastasis by assessing CpG island methylation or expression level of epigenetically regulated differentially expressed coding or non-coding genes. Methods of treatment of human melanoma by modifying or regulating the same pathways are also provided.